The three West African countries at the centre of the Ebola epidemic have recorded their first week with no new cases since the outbreak was declared in March 2014.
More than 11,000 people have died in Guinea, Liberia and Sierra Leone, according to figures from the World Health Organisation (WHO).
It is the worst known occurrence of Ebola in history.
New cases of Ebola have dwindled sharply this year however there are still fears the disease could break out again.
“Over 500 contacts remain under follow-up in Guinea, and several high-risk contacts associated with active and recently active chains of transmission in Guinea and Sierra Leone have been lost to follow-up,” a WHO situation report said.
Sierra Leone released its last known Ebola patients on 28 September but must wait 42 days until it can be declared free of the disease.
Liberia was declared Ebola free on 3 September and Guinea’s most recent cases were recorded on 27 September.